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This is the UK’s strongest evidence yet for vaccine effectiveness.
As part of the analysis, monkeypox cases and vaccination data in England between 4 July and 3 November 2022 were reviewed to identify eligible gay, bisexual and men who have sex with men (GBMSM) cohort, with vaccine coverage in cases compared to a larger eligible population.
Of the 363 cases of monkeypox in this period, 8 were vaccinated at least 14 days earlier and 32 were vaccinated 0 to 13 days earlier. The remainder (323) were not vaccinated during this outbreak. This gives an estimate of vaccine efficacy for a single dose of 78% 14 or more days after vaccination.
UK Health Security Agency (UKHSA) will continue to investigate the duration of protection from single-dose and 2-dose combined protection.
At Jamie Lopez-Bernal, Consultant Epidemiologist UKHSAsaid:
While cases of monkeypox are few, it is important to be aware of the risks. Thanks to those who have already come forward for their vaccine – it is helping to keep the numbers down, but we can’t get complacent.
We now know that a single dose of the vaccine provides strong protection against monkeypox, which shows how important vaccination is to protect yourself and others. A second dose is expected to provide greater and longer-lasting protection.
Please come in for your vaccine as soon as possible – don’t put it off. Remember that it takes 2 weeks for the vaccine to be maximally effective so the sooner you get vaccinated the better.
NHS National Immunization and Screening Director Steve Russell said:
Thanks to the hard-working staff, more than 55,000 doses of the monkeypox vaccine have been distributed so far, and we now know how effective the vaccine is, with just one dose providing 78% protection against the virus.
While the risk of monkeypox remains low, we urge anyone eligible to come forward for their vaccination and with the NHS monkeypox site finder, booking the first dose is now easier than ever, giving yourself the highest level of protection.
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