Henry Ford Health researchers looked at the steroid | Daily News Byte

DETROIT (December 5, 2022) – Results from a study by Henry Ford Health orthopedic researchers are the latest in several high-powered studies focused on effective pain management and reducing the use of opioids. after total knee replacement surgery.

This latest study was a double-blind, randomized, placebo-controlled trial that tested whether oral dexamethasone, a cortisone-like drug or steroid, could reduce pain following total knee arthroplasty (TKA) beyond in a preoperative dose.

The trial investigated the postoperative effects and safety of oral dexamethasone as a potential augmentation in multimodal use in outpatient knee replacement.

“When it comes to supporting our same-day joint replacement patients in ambulatory surgical centers, our research focus is on how to properly manage pain when they go home to reduce the use of opioids as well as unnecessary emergency department visits,” said Jonathan Shaw, MD, chief resident for the Department of Orthopedic Surgery at Henry Ford Health and the study’s lead investigator.

Previous research shows that intravenous dexamethasone following joint replacement surgery reduces pain and the need for opioid use. The focus of this study was to measure the effectiveness of additional dexamethasone taken in a pill form for several days after returning home from outpatient surgery.

“What we found was that while on oral steroids patients reported less pain after surgery as part of their multi-modal regimen,” said Dr. Shaw.

The research team also looked at complications from giving patients steroids after total knee replacement. Within this recruited population, there was no increase in reported difficulty sleeping, surgical healing, or infection.

“This translational research builds on what we know helps prevent nausea after chemotherapy during some cancer treatments and adds to the pain-relieving properties we use after joint surgery. to potentially help in the initial recovery period,” said Jason Davis, MD., an orthopedic surgeon at Henry Ford Health and the study’s senior author.

The novel study was recently presented at the annual meeting of the American Association of Hip and Knee Surgeons (AAHKS) and received the 2022 AAHKS Clinical Research Award. This award is given in recognition of an outstanding clinical role in the field of hip and knee arthroplasty. It was selected from 1,800 clinical research abstracts submitted for presentation; Only 54 were selected for podiums at the association’s annual international conference held in Dallas, Texas last November. The study is planned for publication in the Journal of Arthroplasty in 2023.

“The Department of Orthopedic Surgery is one of the specialties at Henry Ford that has truly adopted a multi-modal pain management model that applies a variety of pain management medications to manage patients’ pain. patients and reduce opioid use,” said Dr. Shaw.

The study is part of Henry Ford’s ongoing, broader initiative launched in 2016 to reduce the number of prescription opioid pills and patches. In 2019, the State of Michigan enacted new laws regulating the prescribing and dispensing of controlled substances including opioid painkillers.

To learn more about orthopedic care and research at Henry Ford Health, visit henryford.com/services/orthopedics.

Study Abstract: AAHKS_2022_ClinicalResearchAward.pdf

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MEDIA CONTACT: Sal Giacona / sgiacon1@hfhs.org / 313-421-9108

ABOUT HENRY FORD HEALTH
Serving communities throughout Michigan and beyond, Henry Ford Health is committed to partnering with patients and members throughout their health journey. Henry Ford Health provides a full continuum of services – from primary and preventive care, to complex and specialty care, health insurance, a full range of home health offerings, virtual care, pharmacy, health care eye and other health care retail.

It is one of the country’s leading academic medical centers, recognized for clinical excellence in cancer care, cardiology and cardiovascular surgery, neurology and neurosurgery, orthopedics and sports medicine, and multi-organ transplants. Consistently ranked among the top five NIH-funded institutions in Michigan, Henry Ford Health engages in more than 2,000 research projects annually. Dedicated to educating the next generation of health professionals, Henry Ford Health trains more than 4,000 medical students, residents and fellows each year in 50+ accredited programs.

With more than 33,000 valued team members, Henry Ford Health is also among Michigan’s largest and most diverse employers, including nearly 6,000 physicians and researchers from Henry Ford Medical Group, Henry Ford Physician Network and Jackson Health Network.

The health system is led by President and CEO Robert G. Riney and serves a growing number of customers at 250+ locations throughout Michigan including five acute care hospitals, two destination facilities for complex cancer and orthopedics and sports medicine care, three behavioral health facilities, primary care and urgent care centers.